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Water is a life-sustaining sector, and adequate access to safe water is fundamental to a healthy life and driving countries’ economic growth. It is an endowment from nature that must be protected and defended. However, the gross negligence and mismanagement of the water bodies, poor sanitation facilities, improper handling of liquid and solid wastes, and uncontrolled population growth pose a severe threat to the freshwater sector in developing economies like India. The widespread presence of healthcare products, pharmaceutically active compounds, and similar unregulated compounds in freshwater is an emerging concern due to their increasing societal dependence. These pollutants are causing additional threats to the dwindling freshwater reserves and posing significant challenges to achieving water quality objectives. The frequency of occurrence of geogenic pollutants, including radioactive pollutants, is also increased due to anthropogenic factors. Though various measures have been taken to address the problem, lack of planning, regulatory guidelines, poor institutional framework, and corruption have hampered the beneficial outcome. As a result, many underprivileged people from rural and urban areas in India and other nations in the Global South still lack access to safe drinking water. Considering the complexity of the problem, a comprehensive approach is needed to improve the existing condition and provide safe water to everyone. This chapter reviews various challenges pertaining to water quality in India and Nepal and solutions to obtain water quality objectives in a sustainable way.

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