It is essential to know the streamflow behavior in hydrological basins for appropriate water resource planning and management. In Colombia, where there is a considerable water resource potential, there is a need to generate hydrological modeling for many ungauged catchments. Thus, this study presents the regionalization of flow duration curves (FDC) in Colombia. Daily flow time series from 655 gauging stations were used to define homogenous hydrological regions, considering geological, topographic, and climatic information. Fifteen hydrological regions were delimited by cluster analysis using the K-means algorithm, all of which exhibited high spatial heterogeneity. Multiple linear regressions were used to estimate characteristic dimensionless flows as a function of each basin's attributes. A set of equations that allow the reconstruction of simulated dimensionless FDC for each cluster was determined, and regression (R2) values of 0.5–0.9 were obtained. The percentage error of the mean, maximum, and minimum discharge of the simulated FDC compared with observed values were approximately 9, 30, and 50%, respectively.

  • Regional equations that allow the estimation of flow regime in Colombia.

  • Definition of hydrological homogeneous regions in Colombia.

  • Hydrological data and parameter analysis for Colombia.

  • More regionalization parameters were included and analyzed.

  • Linear multiple regresions were performed with more than two independent variables.

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