In this work, the results of the application of organic expanded porphyrins in the disinfection of water by the photodynamic inactivation (PDI) technique are presented. The photoinactivation properties of a novel, expanded porphyrin, namely 20-(4-carboxyphenyl)-2,13-dimethyl-3,12-diethyl-(22π) pentaphyrin (PCCox), were tested in the disinfection of water using Staphylococcus aureus as a Gram-positive bacteria model. The data showed that PCCox was effective against S. aureus bacteria at nanomolar concentrations. The variation with irradiation time and concentration was studied using both a multi-LED monochromatic light (λ = 470 nm) and an incandescent light bulb with a wide emission spectrum. A PCCox dosage of 5 μM was sufficient to achieve a 99.997% abatement of S. aureus within 1 h of 40 W/m2 irradiation with monochromatic light (λ = 470 nm), whereas under the same conditions using irradiation with white light, the abatement was 99.9997%.
The photodynamic inactivation of Staphylococcus aureus in water using visible light with a new expanded porphyrin
G. Rossi, D. Goi, C. Comuzzi; The photodynamic inactivation of Staphylococcus aureus in water using visible light with a new expanded porphyrin. J Water Health 1 September 2012; 10 (3): 390–399. doi: https://doi.org/10.2166/wh.2012.034
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