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There are two strategies to start up an AnMBR: (1) using a constant HRT and COD of concentration to start-up; (2) using a constant HRT and gradually increasing the COD concentration to start-up. In accordance with the antibiotic solvent wastewater characteristics, this work used the second strategy, and the specific operating conditions are listed in Table 3.

Table 3

Operating conditions for AnMBR start-up

ItemStart-up
Running days (d) 1–23 
THF concentration of influent (mg/L) 0–100 
DMF concentration of influent (mg/L) 0–300 
MC concentration of influent (mg/L) 0–200 
IPA concentration of influent (mg/L) 0–20 
Influent COD (mg/L) 1,000–3,000 
HRT (h) 48 
COD volume load (kg COD/m3·d) 0.5–1.5 
THF volume load (kg THF/m3·d) 0–0.05 
DMF volume load (kg DMF/m3·d) 0–0.25 
MC volume load (kg MC/m3·d) 0–0.05 
IPA volume load (kg IPA /m3·d) 0–0.01 
Temperature (°C) 35 ± 1 
pH 6.0–8.5 
Sludge age (d) No sludge 
Alkalinity (mg/L) >1,000 
Cross flow rate CFV (m/s) 0.2 ± 0.1 
Transmembrane pressure TMP (kPa) 10–30 
Membrane effluent discharge (L/h) 2.0 
ItemStart-up
Running days (d) 1–23 
THF concentration of influent (mg/L) 0–100 
DMF concentration of influent (mg/L) 0–300 
MC concentration of influent (mg/L) 0–200 
IPA concentration of influent (mg/L) 0–20 
Influent COD (mg/L) 1,000–3,000 
HRT (h) 48 
COD volume load (kg COD/m3·d) 0.5–1.5 
THF volume load (kg THF/m3·d) 0–0.05 
DMF volume load (kg DMF/m3·d) 0–0.25 
MC volume load (kg MC/m3·d) 0–0.05 
IPA volume load (kg IPA /m3·d) 0–0.01 
Temperature (°C) 35 ± 1 
pH 6.0–8.5 
Sludge age (d) No sludge 
Alkalinity (mg/L) >1,000 
Cross flow rate CFV (m/s) 0.2 ± 0.1 
Transmembrane pressure TMP (kPa) 10–30 
Membrane effluent discharge (L/h) 2.0 

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