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The susceptibilities of L. pneumophila sg 1, L. pneumophila non-sg 1, total L. pneumophila, and non-L. pneumophila isolates to the eight tested antimicrobials are shown in Table 3. No differences were found between L. pneumophila sg 1 and non-sg 1 isolates for any of the eight antibiotics. In addition, no differences were found between L. pneumophila and non-L. pneumophila for six of the antibiotics (AZM, CIP, ERM, MIN, LEV, and MOX). In contrast, MIC values for CTX and DOC were significantly lower in non-L. pneumophila than in L. pneumophila isolates.

Table 3

MIC values (mg/L) for L. pneumophila sg 1, L. pneumophila non-sg 1, total L. pneumophila, and non-L. pneumophila

 L. pneumophila sg 1
L. pneumophila non-sg 1
L. pneumophila
non-L. pneumophila
DrugsMIC50MIC90GMMIC50MIC90GMMIC50MIC90GMMIC50MIC90GM
AZM 0.062 0.25 0.129 0.062 0.5 0.093 0.062 0.25 0.103 0.062 0.5 0.166 
CTX 3.364 16 4.203 3.931 1.495 
CIP 0.031 0.031 0.023 0.031 0.062 0.026 0.031 0.031 0.025 0.031 0.031 0.027 
DOC 16 5.993 16 8.406 16 7.595 5.278 
ERM 0.125 0.25 0.151 0.25 0.5 0.205 0.125 0.5 0.187 0.125 0.5 0.219 
LEV 0.031 0.031 0.020 0.016 0.031 0.020 0.016 0.031 0.020 0.031 0.031 0.029 
MIN 2.378 3.534 3.138 3.364 
MOX 0.031 0.062 0.025 0.031 0.062 0.032 0.031 0.062 0.030 0.031 0.062 0.035 
 L. pneumophila sg 1
L. pneumophila non-sg 1
L. pneumophila
non-L. pneumophila
DrugsMIC50MIC90GMMIC50MIC90GMMIC50MIC90GMMIC50MIC90GM
AZM 0.062 0.25 0.129 0.062 0.5 0.093 0.062 0.25 0.103 0.062 0.5 0.166 
CTX 3.364 16 4.203 3.931 1.495 
CIP 0.031 0.031 0.023 0.031 0.062 0.026 0.031 0.031 0.025 0.031 0.031 0.027 
DOC 16 5.993 16 8.406 16 7.595 5.278 
ERM 0.125 0.25 0.151 0.25 0.5 0.205 0.125 0.5 0.187 0.125 0.5 0.219 
LEV 0.031 0.031 0.020 0.016 0.031 0.020 0.016 0.031 0.020 0.031 0.031 0.029 
MIN 2.378 3.534 3.138 3.364 
MOX 0.031 0.062 0.025 0.031 0.062 0.032 0.031 0.062 0.030 0.031 0.062 0.035 

GM, geometric median.

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