As shown in Table 4, the susceptibilities of Legionella strains isolated from Guangzhou and Macau to the eight tested antimicrobials were compared. No differences were found between Guangzhou isolates and Macau isolates for three of the antibiotics (CTX, DOC, and MIN). In contrast, MIC values for AZM, CIP, ERM, LEV, and MOX were significantly lower in Guangzhou isolates than in Macau isolates.

Table 4

MIC values (mg/L) for Legionella from Guangzhou and Macau

 Guangzhou
Macau
DrugsMIC50MIC90GMMIC50MIC90GM
AZM 0.034 0.068 0.049 0.25 0.5 0.148 
CTX 4 8 4 4 8 2.639 
CIP 0.017 0.034 0.018 0.034 0.068 0.027 
DOC 8 16 9.075 8 16 6.290 
ERM 0.125 0.25 0.142 0.25 0.5 0.212 
LEV 0.017 0.034 0.017 0.034 0.034 0.024 
MIN 4 8 3.526 4 8 3.145 
MOX 0.017 0.068 0.022 0.034 0.068 0.034 
 Guangzhou
Macau
DrugsMIC50MIC90GMMIC50MIC90GM
AZM 0.034 0.068 0.049 0.25 0.5 0.148 
CTX 4 8 4 4 8 2.639 
CIP 0.017 0.034 0.018 0.034 0.068 0.027 
DOC 8 16 9.075 8 16 6.290 
ERM 0.125 0.25 0.142 0.25 0.5 0.212 
LEV 0.017 0.034 0.017 0.034 0.034 0.024 
MIN 4 8 3.526 4 8 3.145 
MOX 0.017 0.068 0.022 0.034 0.068 0.034 

GM, geometric median.

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