Table 1

Pooled odds ratios for cholera risk factors – adjusted for multiple studies within the same papera

Risk factor categoryRisk factorORLower 95%CIUpper 95%CIP-value
Water treatment Untreated water 2.80 1.82 4.29 <0.001 
Boiling 0.44 0.33 0.60 <0.001 
Chlorination 0.47 0.23 0.98 0.043 
Water source All Municipal/piped 0.90 0.42 1.95 0.790 
Municipal/piped – no waterborne outbreak 0.42 0.26 0.70 0.001 
Surface water 2.88 1.69 4.90 <0.001 
Rainwater 0.34 0.21 0.60 <0.001 
Well water 3.01 1.08 8.39 0.035 
Sanitation Open defaecation 2.64 1.58 4.39 <0.001 
Shared facilities 1.82 1.33 2.51 <0.001 
Improved sanitation 0.69 0.44 1.08 0.110 
Hand hygiene All handwashing 0.36 0.25 0.52 <0.001 
Handwashing before food 0.45 0.32 0.65 <0.001 
Handwashing after defaecation 0.28 0.17 0.45 <0.001 
Presence of soap 0.31 0.22 0.45 <0.001 
Water storage Narrow-mouthed container 0.61 0.12 3.10 0.550 
Other containers 2.02 1.15 3.57 0.015 
Risk factor categoryRisk factorORLower 95%CIUpper 95%CIP-value
Water treatment Untreated water 2.80 1.82 4.29 <0.001 
Boiling 0.44 0.33 0.60 <0.001 
Chlorination 0.47 0.23 0.98 0.043 
Water source All Municipal/piped 0.90 0.42 1.95 0.790 
Municipal/piped – no waterborne outbreak 0.42 0.26 0.70 0.001 
Surface water 2.88 1.69 4.90 <0.001 
Rainwater 0.34 0.21 0.60 <0.001 
Well water 3.01 1.08 8.39 0.035 
Sanitation Open defaecation 2.64 1.58 4.39 <0.001 
Shared facilities 1.82 1.33 2.51 <0.001 
Improved sanitation 0.69 0.44 1.08 0.110 
Hand hygiene All handwashing 0.36 0.25 0.52 <0.001 
Handwashing before food 0.45 0.32 0.65 <0.001 
Handwashing after defaecation 0.28 0.17 0.45 <0.001 
Presence of soap 0.31 0.22 0.45 <0.001 
Water storage Narrow-mouthed container 0.61 0.12 3.10 0.550 
Other containers 2.02 1.15 3.57 0.015 

aBrief methods for obtaining odds ratios in the ‘Methods’ section, full methods detailed in Supplementary file 1.

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