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Table 6

ANOVA results for the response surface quadratic model

SourceSSdfMSF-ValueP-Value
Model 0.020 14 1.420 × 10−3 44.74 <0.0001 Significant 
A-N 1.716 × 10−4 1.716 × 10−4 5.41 0.0356  
B-NF 1.681 × 10−4 1.681 × 10−4 5.30 0.0372  
C-D 0.016 0.016 491.58 <0.0001  
D-R 1.060 × 10−3 1.060 × 10−3 33.41 <0.0001  
AB 3.112 × 10−5 3.112 × 10−5 0.98 0.3388  
AC 3.555 × 10−6 3.555 × 10−6 0.11 0.7428  
AD 6.547 × 10−5 6.547 × 10−5 2.06 0.1728  
BC 3.649 × 10−6 3.649 × 10−6 0.12 0.7395  
BD 6.408 × 10−5 6.408 × 10−5 2.02 0.1772  
CD 1.707 × 10−5 1.707 × 10−5 0.54 0.4754  
A2 1.721 × 10−5 1.721 × 10−5 0.54 0.4736  
B2 1.780 × 10−5 1.780 × 10−5 0.56 0.4663  
C2 2.589 × 10−3 2.589 × 10−3 81.61 <0.0001  
D2 2.204 × 10−4 2.204 × 10−4 6.95 0.0196  
Residual 4.442 × 10−4 14 3.173 × 10−5    
Lack of Fit 4.155 × 10−4 10 4.155 × 10−5 5.78 0.0527 Not significant 
Pure Error 2.874 × 10−5 7.184 × 10−6    
R2 0.9781      
Radj2 0.9563      
SourceSSdfMSF-ValueP-Value
Model 0.020 14 1.420 × 10−3 44.74 <0.0001 Significant 
A-N 1.716 × 10−4 1.716 × 10−4 5.41 0.0356  
B-NF 1.681 × 10−4 1.681 × 10−4 5.30 0.0372  
C-D 0.016 0.016 491.58 <0.0001  
D-R 1.060 × 10−3 1.060 × 10−3 33.41 <0.0001  
AB 3.112 × 10−5 3.112 × 10−5 0.98 0.3388  
AC 3.555 × 10−6 3.555 × 10−6 0.11 0.7428  
AD 6.547 × 10−5 6.547 × 10−5 2.06 0.1728  
BC 3.649 × 10−6 3.649 × 10−6 0.12 0.7395  
BD 6.408 × 10−5 6.408 × 10−5 2.02 0.1772  
CD 1.707 × 10−5 1.707 × 10−5 0.54 0.4754  
A2 1.721 × 10−5 1.721 × 10−5 0.54 0.4736  
B2 1.780 × 10−5 1.780 × 10−5 0.56 0.4663  
C2 2.589 × 10−3 2.589 × 10−3 81.61 <0.0001  
D2 2.204 × 10−4 2.204 × 10−4 6.95 0.0196  
Residual 4.442 × 10−4 14 3.173 × 10−5    
Lack of Fit 4.155 × 10−4 10 4.155 × 10−5 5.78 0.0527 Not significant 
Pure Error 2.874 × 10−5 7.184 × 10−6    
R2 0.9781      
Radj2 0.9563      

Note: df, degree of freedom; MS, mean square; SS, sum of squares.

*P-value <0.05 indicates statistical significance.

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