Sustainable reuse of human excreta in socially and religiously conservative societies is extremely difficult. People's perceptions and acceptability regarding the reuse of human excreta is mainly linked to their culture. In addition, certain societies regard the cultural and social barriers more than the religious barriers. The aim of this study is to understand the perceptions of people about the reuse of human excreta for agricultural purposes. Qualitative research methods were used for data collection. Farmers in the village recognized the importance and economic benefit of reusing human excreta. They accepted the reuse of human excreta on their farms only if they were supplied with a treatment facility. Contrary to the farmers, the local community showed reluctance in reusing human excreta while recognizing the nutritional value of it. It was therefore concluded that the main barrier in sustainable and safe re-use of human excreta lies in socio-cultural and religious foundations of traditional societies like Kakul village in Abbottabad District.