This article presents a calibration procedure for a model describing the role of NOM during ozonation. Calibration has been conceived as practical tool for engineering purpose. Using a single-phase batch protocol, two waters were investigated following experimental plans comprising 32 and 14 experiments. Results of the simulations show that the calibration procedure enables the model, for both waters, to predict well changes in ozone dose, temperature and pH, even when a radical scavenger, tert-butanol, is added. More than 70% of the experiments could thus be modelled satisfactorily (predictions statistically classified as “good” or “very good”), having used only 26% of the experiments in calibrating the model. Results obtained for experiments performed at low NOM concentration are more contrasted, however the model is able to account for most changes in sub listed experimental parameters.

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