Progress on legal and practical aspects on water reuse with emphasis on drinking water – an overview

The present study highlights the evolution, the progress and the prospects of future practices of water reuse in the world. The objective was to produce a comprehensive timeline on the global evolution and progress of water reuse. This was achieved through the analysis of the state of the art on the subject. The present study is a qualitative research, where three aspects have been considered to highlight the global evolution of water reuse: i) Regulations, Standards, Criteria or Guidelines (RSCG); ii) Indirect Potable Reuse Projects (IPR); and iii) Direct Potable Reuse Projects (DPR). The study focused on both legal and practical aspects of water reuse and considered 3 timelines in the context of RSCG, IPR and DPR: 29 RSCG instruments, institutionalized from 1918 to 2020, where only 4 instruments were solely dedicated to drinking water reuse; 10 IPR projects; 5 DPR projects. To achieve good, effective results, the regulatory framework must support the objectives of a structured water reuse policy in addition to guaranteeing legitimacy and maintaining public confidence. Integrated water and wastewater management, based on technological and scientific advances, has become a relevant aspect for implementation of more adequate measures by decision makers to address future global water challenges.


INTRODUCTION
Recognition of water and sanitation as a human right by the United Nations (UN) has globally influenced advances in policies that promote improvements in availability, physical accessibility, quality/safety and acceptability of water and sanitation services (UN 2010). However, several challenges still exist and there is great inequality between developed and developing countries (JMP 2019). Global statistics show that 5.3 billion people have access to safe drinking water while 3.4 billion have adequate sanitation. Half of the global population has available facilities to wash their hands with soap (JMP 2019). Remarkably, lack of sanitation generates an average economic loss of 1.3% of world GDP (WHO & UNICEF 2020). Apart from physical scarcity, water quality is a risk factor for drinking water supply and human health. River water pollution in urban areas is attributed to discharge of untreated sewage.
It is in this perspective and desire to change this global framework that water, and sanitation theme appears to be crosscutting in all sustainable development goals and is prominent in SDG6 -ensuring availability and sustainable management of water and sanitation for all. By setting targets and indicators to be achieved by 2030, SDG6 represents an important driver of the universalization of water and sanitation in the world, by reducing future global risks and similarly strengthening the right to water and sanitation. Tortajada (2020) reinforces the importance of reuse for potable and non-potable purposes to achieve the goals established for the SDGs.
Water reuse has been practiced since the pre-historic era. Nowadays it is mainly used for irrigation, industrial water supply and indirect potable reuse. Angelakis et al. (2018) compiled the evolution for 5 periods as described: • In Prehistoric times (ca. 3200-1000 BC), the first indications of the utilization of wastewater for irrigation and fertilization of agricultural lands extended back ca. 5,000 years to the Bronze Age civilizations (e.g., Minoan and Indus Valley).
• In Historical times (ca. 1000 BC-330 AD), some temples of Ancient Greece (Acropolis and Agora) already had wastewater and rainwater for irrigation and fertilization of orchards and agricultural fields.
• During Medieval times (ca. 330 AD-1400 AD), Europe was preoccupied with wars and there was little focus on improving water and sanitation services.
• In the Modern times (ca. 1400 AD-1900 AD), great epidemics in several regions in the world, led the authorities to recognize the need for safe drinking water and sanitation. Thus, sewage farms have gained space across the world, with the use of sewage in agricultural fields. At that time, the practice was understood as wastewater treatment and in view of the accelerated population growth, a new interest in more compact sewage treatment technologies emerged.
• In the Contemporary times (1900 AD-present), significant technological and scientific innovations along with a marked growth in the implementation of wastewater treatment plants (WWTPs) could handle large volumes of wastewater for Water Supply Vol 00 No 0, 2 Uncorrected Proof direct discharge to waterways and the ocean. However, water reclamation and reuse has regained popularity because the challenges of population growth, megacities urbanization and climate change.
Windhoek was the first city in the world to introduce planned potable reuse after it became apparent in the early 1950s that within 10 years, serious water problems would arise in the city due to limited natural water resources (Scientiae 1969). The Groundwater Replenishment System in Southern California launched in 2008 is the world's largest advanced water purification system for potable reuse. In Singapore, NEWater has grown from a demonstration-scale project to a sustainable water source able to meet 40% of the country's water needs and is projected to meet up to 50% of future water needs (Kog 2020). In South Africa, a state-of-the-art advanced water treatment plant (WTP) was commissioned to treat the acid mine water that has been accumulating from the mines in Emalahleni, an industrial town surrounded by coal producing mines, steel manufacture and coal-fired power stations. The town's water security had been threatened by low water quality due to high amounts of dissolved metals and salts accumulating in the catchment (Naidu 2012).
Potable water reuse provides a cost-efficient option to provide a renewable and resilient drinking water supply. Wastewater reuse is a growing practice in the world, especially in countries or regions experiencing water shortages such as the United States of America (USA), Australia, Israel, Western Europe and Mediterranean Region). Frijins et al. 2016 claim that the production of drinking water from reclaimed water has a lower cost when compared to the cost of importing water from neighboring and more distant areas. It is for this reason that some regions have adopted potable reuse since their closest sources are increasingly polluted.
The objective of the paper is to produce a comprehensive timeline on the global evolution and progress of water reuse. Given the difficulty in performing a complete approach to the practice of different modalities of non-potable reuse in the world, the paper focused on the practical aspects with respect to potable uses only. Potable reuse requires advanced technology to produce reclaimed water of acceptable quality. Thus, in order to illustrate the practical advances of water reuse in the world, a timeline on the main potable reuse plants currently operational in the world was presented in addition to the timeline on the regulatory framework.

METHODS
This paper intends to comprehend existing knowledge (without conducting an exhaustive review of the literature), in order to identify points of consensus, controversy and gaps related to the evolution of the practice of water reuse in the world. The experience acquired by different regions of the world were considered, in both legal and practical aspects. Examples and experiences throughout the 5 continents, (Africa, Australia, Europe, Latin America and the USA) were described.
Water reuse is mainly used for irrigation purposes. There are few facilities and regulations for potable reuse. The paper highlights facilities for drinking water (IPR and DPR) and all the legal aspects for water reuse that are an essential tool for the regional institutionalization of water reuse practice. Potable water reuse has 2 methods ( Figure 1): Indirect Potable Water Reuse and Direct Potable Water Reuse. The study considered 3 timelines for: i. Regulations, Standards, Criteria or Guidelines (RSCG): is an essential tool for the regional institutionalization of water reuse practice. Regulatory frameworks address legal aspects like mandatory and non-mandatory standards, criteria, or guidelines. Standard is a rule or measure established by an authority; criteria, are the basis for the standards and developed based on available data and scientific opinion; guidelines are voluntary, advisory, and non-enforceable rules that are used prior to development of standards or regulations; regulation is when the criteria or guidelines are officially adopted as a law. ii. Indirect Potable Water Reuse Projects (IPR): involves the dilution of the treated wastewater in the receiving surface water prior to raw water abstraction for treatment and subsequent drinking water distribution. The paper outlines indirect potable reuse projects, currently in operation, or designed for this purpose. iii. Direct Potable Water Reuse Projects (DPR): is when the effluent from the advanced treatment is directly sent to the WTP or the drinking water distribution system. The timeline for the direct potable reuse projects currently in operation or designed for this purpose has been produced.

RESULTS AND DISCUSSION
The results have been presented separately for (1) RSCG, (2) IPR and (3) DPR. The timeline for RSCG spans up to 2020 whilst the timelines for facilities stretch up to 2014/2015 only. This is because regulations are continuously updated, and hence most recent instruments are available. For facilities, planning and construction of projects can take even up to ten years before project completion. Whilst it may seem like there are no recent projects in DPR and IPR, on the ground, projects may still be in the implementation process whilst the timeline considers projects currently in operation. Each of the 3 aspects (RSCG, IPR and DPR) is described extensively after the respective timeline. Future challenges have also been discussed at the end of the section. The countries and/or states included in the present study, in terms of legal aspects (RSCG) and the distribution of IPR and DPR projects are highlighted in Figure 2.  The timeline about RSCG can be observed in Figure 3. The documents discussed here have been updated continually and cited by many authors. Thus, to facilitate understanding, updates and other specific features can be seen in supplementary materials.
The first regulation in the world was in the State of California/US, in 1918, although water reuse guidelines for the whole country were only established in 1980 (with updates in 1992, 2004 and 2012), by the United States Environmental Protection Agency (US EPA). These guidelines are non-mandatory and not binding on water reuse utilities (Shoushtarian & Negahban-Azar 2020). Lahnsteiner et al. (2018) highlight that the guidelines of Namibia were published in 1998 whilst Australia published guidelines almost one decade later (2006) although Khan & Anderson (2018)  Although China implemented initial water reuse criteria in 2002 (Chen et al. 2017), specific regulations for water reuse were only published in 2008 (Shoushtarian & Negahban-Azar 2020). Five years later, in 2013, the overall rate of water reuse in China's urban areas was around 12% (Chen et al. 2017). According to Liao at al. (2021), wastewater treatment and reclaimed water are not well developed in most Asian countries and regions. Nevertheless, China is the biggest user of reclaimed water globally, with water reuse quantity of 7.1 billion m3/year in 2017, followed by the U.S., which reused 6.63 billion m3 /year of water in 2018 (Liao et al. 2021). From 2009 to 2015, the amount of reclaimed water use in China increased rapidly, but still accounted for less than 1% of total water consumption (Zhu & Dou 2018;Qu et al. 2019). In Brazil, the water reuse rate of treated wastewater is 1.5%, whilst Portugal has an almost similar value of around 1.2% , and the USA has approximately 1% (Mukherjee & Jensen 2020). However, Lima et al. (2020) indicate that all the treated wastewater flow rates in Brazil (with organic matter removal efficiency greater than 80%) represent 9% of the total irrigation water demand in the country. Israel, with the first water reuse regulation published in 1952 ( Jeong et al. 2016), 87% of treated wastewater is reused, representing 40% of water demand for irrigation in the country (Marin et al. 2017).
Based on a request from Israel for water reuse in agriculture, the first International Organization for Standardization (ISO) standards were issued in 2010; the next ISO standard for water reuse was proposed by Japan and were to be established alongside with Israel and China, in 2015 (Shoushtarian & Negahban-Azar 2020). In 2020, ISO published a series called 'Guidelines for treated wastewater use for irrigation projects, divided in 4 parts (ISO 2020). It is important to highlight that the series published by ISO in 2020, suggests an approach called 'fit-for-purpose' which involves the production of reclaimed water of adequate quality to the needs of the end users. ISO aims to encourage the development of regulations and documents compatible with the reality of each country (Rebelo et al. 2020).
The World Health Organization (WHO) has played a very important role in establishing global regulatory documents which are particularly important for the regions with water scarcity and low socio-economic development, such as Latin America, The Caribbean, Asia, and Africa. Many countries have adopted WHO guidelines, modifying them according to their geographical, economic, and epidemiological idiosyncrasies ( Jeong et al. 2016).
Large territorial countries like Brazil, USA, Australia and Canada inevitably end up setting different standards for each state or county, considering their distinct administrative and institutional organization. Additionally, Brazil, USA and Australia have defined non-mandatory guidelines at national level, to guide the strategic planning of states, counties and municipalities. However, the Canadian context lacks foundational guiding documentation and adequate policy on water resources recovery, considering wastewater as a resource, with community engagement (Nixdorff et al. 2021).
In the USA, 28 out of 48 states had adopted specific guidelines for water reuse by 2017 (Shoushtarian & Negahban-Azar 2020) whilst in Brazil, only 5 out of 26 states had published regulations with water quality standards by 2010 . In 2017, Brazil introduced a national program called Interáguas which defined water reuse guidelines, although they have not achieved results as expected. .
Generally, it has been observed that the globally, water reuse regulations have evolved around three main aspects: i. Effects of climate change, surface water pollution and increased water consumption due to population growth require strategic planning by the government to incorporate alternative water sources into existing water matrices. This type of planning action only becomes effective through the enactment of regulatory instruments with safe standards, guidelines, and paths for the institutionalization of practice. ii. Remarkably, it is important to note that the initial actions were taken by regions with water shortages, like the state of California (USA), Israel, Namibia, Australia, and the Mediterranean countries. However, different regions have taken different paths, depending on their specific characteristics and factors of socio-economic development. Israel has consolidated itself worldwide with substantial knowledge regarding the reuse of water in agriculture, while Namibia, California and Australia have chosen to move towards adopting standards for potable reuse. iii. Many regions started their regulatory processes with flexible standards and for less noble specific purposes, due to limited scientific knowledge about the impacts of reuse actions on the public health and the environment. To incorporate technological advances and the emergence of new water demands, the regulations have been updated. For example, according to Olivieri et al. (2020), in the state of California, even before the enactment of the 1918 reclaimed water regulations it was reported in 1910 that there were 35 California communities using sewage for farm irrigation, 11 without any treatment and 24 after septic tank treatment (Ongerth & Jopling 1977). Over the years, the state regulation started to incorporate scientific and technological advances, setting more restrictive criteria and new crops for irrigation (1968), more restrictive criteria for landscape irrigation in unrestricted areas, and even for aquifer recharge (1978), eventually adding criteria for indirect potable reuse with aquifer recharge (2014) and surface water augmentation (2018) (Olivieri et al. 2020).

Indirect potable water reuse projects
The timeline of Indirect Potable Water Reuse Projects is shown in Figure 4. Initially, water reuse practice in the world progressed with advances in technology, regulation, and increase in water and sanitation services demand.
Recently, the availability of alternative sources of drinking water supply such as reuse and desalination, has increased considerably since traditional sources of water (surface and underground) have become increasingly polluted (Mukherjee & Jensen 2020). However, at a global scale, indiscriminate and unplanned schemes of indirect potable reuse are practiced, known as de facto potable reuse. According to Angelakis et al. (2018) 'de facto potable reuse' also referred to as unplanned drinking reuse is defined when a source for drinking water follows a wastewater discharge upstream. The wastewater released represents a significant part of the flow of receiving water bodies. Dalezios et al. (2018) claim that in some drinking WTPs, especially under low-flow conditions, a significant proportion (up to 75%) originated as wastewater effluent from upstream communities. Table 1 shows a summary of the IPR projects characteristics referred in this study.  • The Occoquan/FairFax Virginia (OFFV), implemented in 1978, was the first project of surface water augmentation from treated wastewater in the USA and is considered the most relevant in terms of regional collaboration. In this case, treated wastewater with a high degree of purification, collected from the metropolitan area of Washington D.C., is discharged into the Occoquan Reservoir, upstream from the Fairfax WTP in Virginia (EPA 2012; Sanchez-Flores et al. 2016). Furthermore, • The Orange County Groundwater Replenish System (OCGRS) is the largest water reuse facility of IPR in the world. It started aquifer recharge operation in 1976 and is in operation since 2008 applying the most advanced treatment technologies (Reny et al. 2021). The complete project has a complex reuse scheme which involves the advanced water purification facility in Fountain Valley and produces 378.5 million liters per day of highly treated potable-quality water from secondary treated wastewater effluent provided by the Orange County Sanitation District (Reny et al. 2021). Purified water from an advanced treatment process is infiltrated into the aquifer through injection wells, spreading ponds, and pipeline transmission system, in north/central Orange County (Reny et al. 2021), where the mixture serves as a source of water supply for more than 850,000 people (Tortajada 2020)  • According to Frijins et al. (2016), the Torreele Water Reuse Scheme (TWRS), located in the Belgium south-west coast in operation since 2002, produces high-quality water from the WWTP Wulpen effluent for artificial aquifer recharge. The abstracted groundwater is used to drinking water supply. In this case, 40% (approximately 60,000 inhabitants) of the community's water consumption is derived from the reuse (Tortajada 2020). Also, installation of a subsurface wetland system for treating reverse osmosis concentrate from the Torreele Water Reuse Plan is operating in pilot scale since 2011. The aim is to reduce permit fees associated with the discharge of nutrients and metals to the North Sea (Scholes et al. 2021).
• El Porto de la Selva is a small and tourist town with less than a thousand of inhabitants, in Spain. Nevertheless, during the summer months, the population increases by a factor of four, leading to rapid decline in groundwater levels of local aquifers with limited capacity (Fajnorová et al. 2021). Current tertiary treatment and a non-potable reuse infrastructure was designed for street sweeping, non-agricultural irrigation, and infiltration via the dry riverbed to prevent saltwater intrusion in summer months (Frigola et al. 2015). Since 2015, El Porto de la Selva Groundwater Recharge (EPSGR), during winter months, has been testing regarding its potential to strengthen the local water reuse strategy. It was projected to infiltrate 200 m3 /d of tertiary treated effluent during 200-240 d/yr (outside of the tourism season, i.e., the period from October to May), resulting in 40,000-48,000 m3 /yr additional supply recharged to the groundwater (about 10% of the abstracted groundwater) (Frigola et al. 2015;Fajnorová et al. 2021). According to Fajnorová et al. (2021), the conventional wastewater treatment in El Port de la Selva consists of biological nutrient removal with phosphorus precipitation and secondary clarification. The secondary effluent is further treated in a tertiary treatment plant equipped with dual media filtration and UV disinfection.
In Australia 3 IPR projects deserve to be highlighted: Indirect potable water reuse has been implemented in Singapore over the last 15 years. Until 2018, the reclaimed water, called NEWater, provided an average of 30% of the nation's water demand (Lefebvre 2018); currently, it means 40% and, in the future, 50% (Kog 2020). The original plan called for a greater percentage, but industrial demand for high quality recycled water increased, reducing demand for potable water. This implies that in Singapore, high quality water from advanced wastewater treatment facilities is mainly used in industrial application. The current NEWater production process is a combination of conventional activated sludge, microfiltration or ultrafiltration, reverse osmosis and ultraviolet disinfection (Li et al. 2020). According to Sun et al. (2021), how to improve the environmental sustainability of the NEWater production process towards less sludge generation, reduced energy consumption and small footprint has become an emerging challenge towards future water sustainability.

Direct potable water reuse projects
The timeline of Direct Potable Water Reuse Projects is shown in Figure 5.
Namibia and South Africa operate the main potable reuse plants in the African continent. However, the project operated in Namibia is outstanding for producing safe drinking water for more than 50 years. Hartley et al. (2019) cite surveys carried out in 2010 and 2016 by different institutions which demonstrate acceptance and confidence from consumers.
In the early 1960s, Windhoek, the capital city of Namibia, with almost 400,000 inhabitants, started operating a wastewater treatment plant (Gammams WWTP) capable of producing scientific assessed high-quality effluent for drinking water purposes. During a severe water crisis in 1968, the project was put on a full scale for direct potable reuse. In the 1990s, another severe drought led to the design of a new water reuse facility, which started operating in 2002, increasing the previous Water Supply Vol 00 No 0, 10 Uncorrected Proof capacity by 4.5 times, (Rensburg 2016). It is called the New Gorengab Water Reclamation Plant (NGWRP), and provides, for approximately a quarter of Windhoek's potable water demand (Wallmann et al. 2021). Currently, NGWRP provides water for domestic use (Lahnsteiner et al. 2018), whilst Gammams WWTP still produces reclaimed water for irrigation of public parks and sports fields in the city (Rensburg 2016). According to (Lahnsteiner et al. 2018) the water produced in the NGWRP is mixed directly into the drinking water supply pipe.
Beaufort West Water Reclamation Plant (BWWRP) is operated in South Africa from secondary effluent treatment. The quality of water produced at BWWRP exceeds the national drinking water quality standards. In this way, the water is mixed directly with water treated in the conventional WTP (Lahnsteiner et al. 2018). According to Visser (2021), in January 2011, Beaufort West, a rural area in South Africa, started the implementation of South Africa's first reclamation plant and the project was completed within six months. In this case, treated wastewater effluent is conveyed directly to a water treatment facility for further treatment to attain drinking water standards. This further treatment includes processes such as phosphate removal, pre-disinfection, ultra-filtration, reverse osmosis and advanced oxidation. The plant produces 10,800 L/d of drinking water. The reclaimed water is pumped into a reservoir and blended with water from the Gamka Dam, and 36 boreholes in six aquifers at a ratio of 1:4 (Visser 2021).
In the USA, the only DPR project currently in operation is in the state of Texas, a region known for its low rainfall and arid climate. The region's low water availability has driven the need to implement and operate DPR schemes. According to Wester & Broad (2020), Wichita Falls and Big Spring implemented and operated the first DPR projects in the USA. But currently, only Big Spring is in operation as DPR and Wichita falls operates as IPR. Mukherjee & Jensen (2020) claim that DPR pilot project in US, was in Denver/Colorado/ where a demonstration plant was operated for research and development purposes from 1980 to 1993.
In the city of Wichita Falls the first DPR scheme was considered during a drought in 1990s, although another solution was used until the end of the drought in 2001. Later on, the quality conditions of Lake Kemp (drinking water supply source) required the construction of a microfiltration and reverse osmosis plant in order to treat the increasingly brackish water. The existence of these advanced water treatment facilities was then considered important in decisions to pursue DPR anew. In the latest drought, as levels dropped in Lake Kemp, water quality diminished to the point of being unusable (Wester & Broad 2020).
According to Wester & Broad (2020) and Nix et al. (2021), construction of a project to allow the eventual use of DPR scheme (Wichita Falls Water Reclamation Plant -WFWRP), began in 2013 and was approved in July 2014 on a temporary basis for 6 months. The facility produced approximately 5 MGD, creating a 50-50 blend of treated wastewater and water from surface reservoirs. In July 2015, the DPR plant was decommissioned, after rains replenished reservoirs levels (Lahnsteiner et al. 2018). Occasionally, the secondary effluent from WWTP was sent to the advanced brackish lake WTP, as a Water Reclamation unit. After treatment, the effluent was mixed with raw water abstracted from the brackish water lake (1:1 ratio) for treatment in the conventional WTP using pre-oxidation, coagulation/flocculation, sedimentation, re-stabilization with CO 2 , granular filtration, and chlorination. (Lahnsteiner et al. 2018). After the spring rains of 2015, which were considered sufficient to supply the raw water reservoir, the project was transformed into an IPR (Sanchez-Flores et al. 2016;Lahnsteiner et al. 2018;Wester & Broad 2020;Nix et al. 2021). In addition to transition from DPR to IPR, the city of Wichita Falls implemented a new drought management plan with several strategies, presented as larger portfolio of solutions rather than as alternatives (Wester & Broad 2020).
The Big Spring Water Reclamation Plant -BSWRP started operating in April 2013, producing approximately 2 million gallons of water a day (MGD), which was blended with water from traditional sources at a ratio of 20% reused water to 80% raw water before being distributed to several plants in the immediate region for further conventional treatment prior to public consumption. This project, while relatively small in terms of output and percentage blended compared with proposal that would come later in the state, represented the first successfully implemented DPR system in the USA (Wester & Broad 2020).
Currently, BSWRP is operated from the dechlorinated tertiary effluent of the Big Spring WWTP, mixed with the raw water from the E.V. Spencer reservoir for treatment in conventional WTP and distribution (Lahnsteiner et al. 2018). The reclaimed water is applied directly to the reservoir's raw water pipeline. According to (Sanchez-Flores et al. 2016), the success of the project was mainly attributed to the transparency of the contracted company, the awareness campaign with regulatory agencies and the inevitable reality of water scarcity in the region.
According to Mukherjee & Jensen (2020) WFWRP and BSWRP have been widely accepted by local communities, although Wester & Broad (2020) claim the near absent of discussion of the issue during Big Spring city council meetings. However, there has been cases of vociferous opposition towards projects in San Diego, East Valley (Los Angeles) and Tampa city (Florida) which involved similar technologies, mainly because of management and communication approaches. As of 2017, there were few DPR plants in study, planned, in demonstration scale or approved but not yet constructed in US. Table 2 shows a summary of DPR projects characteristics referred in this study.
In terms of technology, the process to produce DPR water is long and involves a combination of stages that include (i) physicochemical: coagulation-flocculation; (ii) conventional filtration: sand and carbon filtration (biological and activated granular); (iii) membrane advanced filtration: micro filtration, ultrafiltration, and reverse osmosis; (iv) advanced oxidation process: UV-peroxide and ozonization; (v) disinfection: chlorination, UV and lagoon. Wallmann et al. (2021) claim that the technologies used in combination, called multi-barrier system can remove specific contaminants for the drinking water safety, as coliform bacteria, antibiotic-resistant bacteria, and antibiotic resistance genes.

Future challenges
Despite the great advances in regulation and application of water reuse in the world, there are many challenges that still need to be addressed: (a) Integrated water and wastewater management: when planning, it is important to consider water and wastewater in an integrated approach unlike the current situation where water resources management issues are still regarded separately from sanitation issues. The concept 'One water', which characterizes the merger between the two units, leads to more thoughtful, rational, and economical solutions that can be implemented to meet future water needs (Angelakis et al. It is therefore important to align them to protect public health, the environment, and the global future economy. It is also important to develop comprehensive and flexible solutions, in addition to a regulatory framework together with an efficient water reuse policy based on more realistic risk assessments (Rebelo et al. 2020) so that the approach can be applied safely, responsibly, and systemically. (c) Planning and investments in low-and middle-income countries: The regions with low socio-economic development usually get international support (both legal and technical) that often does not match their local realities and needs.
Santos & Vieira (2020) emphasize that it is important for the regulatory framework to align with respective local experiences and planning should be the driver of reuse activities in the regions most affected by drought. (d) Minimization of rejection (Factor Yuck): As highlighted by Mukherjee & Jensen (2020) the psychological barrier of rejection, known as 'Yuck Factor' is one of the main challenges associated with the difficulty in implementing the practice of water reuse, especially for drinking water projects. Thus, a transparent approach with the receiving communities is necessary, in addition to the implementation of pilot projects to instill trust between the producer and the user of the water reuse ( technological advances for wastewater treatment have been more striking in the contemporary period especially in the last three decades. These advances have even allowed the adoption of the practice of potable reuse. However, Tsagarakis et al. (2013) emphasize that adequate attention must be given to the quality of water reuse produced by different wastewater treatment technologies, considering that effluents from primary wastewater treatment technologies can be applied in forested lands and parks in a controlled manner. The best quality of water reuse is not only obtained from advanced technologies and high costs, but simple low-cost technologies can also be adopted for non-potable uses where the microbiological risk is lower. Figure 6, shows the integration between the presented challenges and the actions needed to allow and boost the systematic practice of water reuse CONCLUSION The evolution in the last century of the legal and practical aspects of water reuse in the world was outlined. The criteria used in regulation were initially adopted for non-potable applications such as agricultural and irrigation uses. Over the years, technological advances have facilitated the production of better-quality reclaimed water to meet rising drinking water demands due to population growth, and climate change. Thus, the regions most affected by water shortages started their indirect and direct potable reuse projects, according to their specificities and idiosyncrasies.
Currently, it is possible to affirm that water reuse can be a safe practice if the correct paths are adopted to guarantee the safety of public health and the protection of the environment. Many issues still need to be addressed, especially in regions with low socioeconomic development, with challenges in planning, investments, and regulations. Developing countries need to learn from the paths taken by the developed regions to establish more flexible standards, which consider local circumstances whilst adjusting to the development of new technologies and new demands. The initial step is very crucial. To achieve good, effective results, the regulatory framework must support the objectives of a structured water reuse policy in addition to guaranteeing legitimacy and maintaining public confidence. Integrated water and wastewater management, based on technological and scientific advances, has become a relevant aspect for implementation of more adequate measures by decision makers to address future global water challenges.

FUNDING
This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

DATA AVAILABILITY STATEMENT
All relevant data are included in the paper or its Supplementary Information.