LT50 values obtained for Monodontaturbinata exposed to heavy metal ions were as follows: 25.2 days after exposure to final concentration of 1.0ppm Cd+2; 21.2 days for 0.1ppm Hg+2; 25.2 for 0. 5ppm Cr+3 and 16.8 days for 0.5ppm Cr+6, compared to 32.8 days for the control. The final concentrations of metal ions in the mollusc tissue increased by 20 times in the Hg+2, and by 10 times in the Cd+2 treated Monodonta, compared to the untreated control. The normal contents of cytochromes be and P450 in Monodontaturbinata digestive gland microsomes were 195±51 and 58±20 nmol/mg protein, respectively. NADPH-cytochrome c reductase activity was 5.9±3.0 nmol/min/mg protein. Exposure to all heavy metal ions had a destructive effect on the two hemoproteins, especially on cytochrome P450, and a pronounced impact on NADPH-cytochrome c activity which was reduced to about 50% in the treated mollusc. No alarming concentrations of metal ions could be detected in Monodontaturbinata collected from different sites along Israel Mediterranean coast.
The Effects of Exposure to Heavy Metal Ions on Cytochrome b5 and Components of the Mixed-Function Oxidases from the Digestive Gland Microsomes of the Mollusc Monodonta turbinata
R. Manelis, H. Hornung, L. Fishelson, A. Yawetz; The Effects of Exposure to Heavy Metal Ions on Cytochrome b5 and Components of the Mixed-Function Oxidases from the Digestive Gland Microsomes of the Mollusc Monodonta turbinata. Water Sci Technol 1 April 1993; 27 (7-8): 473–480. doi: https://doi.org/10.2166/wst.1993.0584
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