The purpose of this study was to design the water quality monitoring network of the Keelung River which was channel regulated recently. A steady-state water quality model was used to simulate the BOD and DO curves. Kriging theory was applied for selecting the optimal locations of water quality monitoring network. The sampling frequency was determined by variances of water quality, considering the significant level and confidence interval. The optimal results indicated that more monitoring stations are needed in the downstream reaches. The stations suggested in the total number of monitoring network of the Keelung River is twenty-one, and the sampling frequency needs to be about two or three times per month.

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