Detection and origin of 3-chloro-4-dichloromethyl-5-hydroxy-2(5H)furanone (MX) in river water Available to Purchase

An isolation experiment of MX, a potent mutagen and promoter in drinking water, from river water contaminated with industrial and domestic sewage was carried out. The presence of MX was demonstrated by GC-MS-SIM method. The contribution ratio of MX to the total mutagenic activity of river water was 5–30%. To elucidate the origin of MX, several chemicals contained in domestic sewage were treated with sodium hypochlorite. From each reaction solution of catechin mixture, catechin and diosmin, MX was isolated and identified. These contribution ratios to the total mutagenicity of each reaction mixture were 36.3%, 95.5% and 4.3%, respectively. The results suggest that domestic sewage is a new origin of MX.