Sediment deposition in sewers and urban drainage systems has great effect on the hydraulic capacity of the channel. In this respect, the self-cleansing concept has been widely used for sewers and urban drainage systems design. This study investigates the bed load sediment transport in sewer pipes with particular reference to the non-deposition condition in clean bed channels. Four data sets available in the literature covering wide ranges of pipe size, sediment size and sediment volumetric concentration have been utilized through applying decision tree (DT), generalized regression neural network (GR) and multivariate adaptive regression splines (MARS) techniques for modeling. The developed models have been compared with conventional regression models available in the literature. The model performance indicators, showed that DT, GR and MARS models outperform conventional regression models. Result shows that GR and MARS models are comparable in terms of calculating particle Froude number and performing better than DT. It is concluded that conventional regression models generally overestimate particle Froude number for the non-deposition condition of sediment transport, while DT, GR and MARS outputs are close to their measured counterparts.