New and alternative sanitation systems are increasingly discussed and find their way into implementation. However, discussions on sanitation concepts often are held in a rather emotional way. Furthermore, not all the available sanitation concepts might be known to the decision maker. The work presented here attempts to contribute to a good discussion and decision making process by compiling available technologies, by defining easy-to-implement criteria for a Sustainability Assessment Method and by integrating these results into a simulation tool which allows to visualise the related resource fluxes (e.g. those on nutrients, such as N, P and K) and to analyse different sanitation options with regard to their capital and operational costs and with regard to environmental impact criteria such as greenhouse gas emissions. Whilst the calculations are to be considered as being approximative in their nature (due to uncertainties or lack of suitable input data), this tool allows the planners, with sometimes little modelling experience, to consider the characteristics of sanitation systems. Whilst starting from earlier work, such as EAWAG's Sanitation Compendium and work on Material Flow Analysis, work described in this contribution merges resource flux modelling, easy-to-use simulation and visualisation and methods of Life Cycle Assessment and Life Cycle Costing. The simulation tool is freely available on https://www.ifak.eu/en/products/sampsons.