Tatu Estuary is an ecological area where economical, cultural, leisure and academic research potentials are enormous. Recent researches indicated that the water quality of the upper streams remained at safety conditions. However, the water body of the downstream sections starting from the outfall of the Taiwan Chemical Fabric Company (TCFC) effluent has been seriously polluted. Due to the effect of tidal flow in this area of the river, it has been very difficult for the accumulated pollutants to dispel and the situation has reached a severe level. This study proposed that legislation should be established in order to reduce and to control the industrial wastes entering the river. To cope with the effort in environmental conservation, it is hoped that water resources of Tatu Chi (River) can be used more effectively.