The first part of a research project to acquire knowledge of the River Meuse has been carried out. It appeared that certain ecological rehabilitation of the Meuse is likely most successful with enhancement of habitats for riverine vegetation, fish and birds. However, the arising of river banks and islands is uncertain because the transport capacity of the river is larger than the actual transport of sediment. Moreover there are still barriers for several macro invertebrates, and risks for waterbirds and mammals, due to eutrofication and presence of micropollutants.