This work describes a novel technology for the reuse of low concentrated electronic wastewater using selected microbe immobilisation cell (SMIC) system. The SMIC system is an innovative technology to maximise the activity of specific microorganisms capable of decomposing tetramethyl ammonium hydroxide (TMAH) as a major organic compound in the low concentrated electronic wastewater. The versatility of the SMIC system has been studied by using continuous-flow reactors. The TOC in a SMIC system was removed completely, indicating that SMIC is a useful technology to remove TOC biologically in low concentrated wastewater. The most important advantages of this system are highly effective and stable in view of TMAH removal. These characteristics make well suited to various applications depending on targeted compounds and microorganisms and, especially, in the wastewater of electronic facilities.