In the Mediterranean region, water scarcity has already prompted concern in the wine sector due to the strong impact it has on vineyard productivity and wine quality. Water footprint is an indicator that accounts all the water involved in the creation of a product and may help producers to identify hotspots, reduce water consumption and the corresponding production costs. In recent years several studies have been reported on wine water footprint determination, but mostly focused on viticulture phase or assuming no grey water footprint at the winery since it has a treatment system. On the framework of WineWaterFootprint project a medium size winery was monitored, with direct measurements, regarding determination of blue and grey components of water footprint. The determined winery water footprint ranged from 9.6 to 12.7 L of water per wine bottle of 0.75 L, being the wastewater produced responsible for about 98%, which means that grey component cannot be disregard. The developed scenarios show that a potential reduction of 87% on winery water footprint can be obtained with almost no investment. The challenge of reducing grey footprint is not at technology development, but rather a proper maintenance and monitoring of treatment systems.